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Discontinuing often leads to gaining back the weight lost while taking the medication
Long-term users often report that benefits plateau and stabilize rather than continuing to increase indefinitely, which is expected given that glutathione's effects are primarily protective and restorative rather than performance-enhancing beyond normal physiological function
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On the other hand, glutathione conjugates of certain substances may be further metabolized into more toxic products
Bisaglia M, Greggio E, Maric D, Miller DW, Cookson MR, Bubacco L
A 2020 randomized clinical trial of 440 individuals with anemia found no difference in iron absorption between the group that took iron with vitamin C and the group that took iron alone
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